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Action in vivo and in vitro of 2-tetradecylglycidic acid, 2-tetradecylglycidyl-CoA and 2-tetradecylglycidylcarnitine on hepatic carnitine palmitoyltransferase

The response to ER stress plays a pivotal role in MTX-induced apoptosis, where MTX primarily triggers ER stress via the PERK/CHOP pathway (Song et al., 2021)

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Together, our findings indicate that GSH synthesis in the liver is a crucial contributor to lipid abundance in vivo

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The cells were plated on collagen-coated 96-well plates at the density of 2 10 4 per well in 0.1 mL DMEM, treated subsequently as described above