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doi: 10.1111/bph.15930 245 CarabottiMSciroccoAMaselliMASeveriC

VFA plays a key role in metabolic and cardiovascular disease

Hydrogen Bond Analysis Hydrogen bond interaction was calculated between the ligands and the protein to understand the interaction evolution of the ligand with the respective proteins

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Reagents and general procedures from the Gibson assembly cloning kit from New England Biolabs (NEB) were used

Oral semaglutide doses included 0.05 mg/kg, 0.12 mg/kg, 0.23 mg/kg, and 0.7 mg/kg, which were equivalent to three, seven, 14, and 42 mg human doses, respectively