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Indeed, aging muscles produce excess TGF- which induces high levels of pSmad3 in satellite cells [22], thus antagonizing Notch and satellite-cell proliferation

Dragonfly confocal microscope system (Oxford Instruments, UK) was used to capture images of the stained rings, and the ImageJ software was used to quantify the number of branches

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Right, dominant-negative Gs is similar to wild-type Gs in binding, but does not bind GTPS