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For most patients, this is four to eight weeks

In another, a lifespan trial in Swiss-derived SHR mice (1 g/mouse per month) reported no changes in food intake or body weight, while chromosomal aberrations decreased and maximum lifespan increased [7]

N Engl J Med, 2006

It's just not worth it

Followed by a maintenance phase of 2 to 4 mg per week for an additional 2 to 4 weeks

Medically reviewed by Chet Tharpe, MDBoard-certified physician Related Articles How Coenzyme Q10 (CoQ10) Interacts with Weight Loss Medications CoQ10 has no direct interaction with semaglutide or tirzepatide, but GLP-1s reduce fat intake and slow gastric emptying, which can lower CoQ10 absorption