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STEP-5 extended follow-up to 104 weeks and found that patients who continued semaglutide maintained a 15.2% mean weight reduction, while those who switched to placebo regained roughly two-thirds of lost weight by week 104
Feeling the GLP-1 Gut Shift
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Compared to patients treated for diabetes with a non-GLP-1 medication, GLP-1 use was associated with 14% reduced risk of developing any substance use disorder
However, the process of making ATP also produces reactive oxygen species (ROS), such as hydrogen peroxide, which can damage the cell at higher levels
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