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for others, it may subtly influence hunger cues or side effects

Chen, Y., et al

Similar long-term data for oral formulations is currently unavailable

Pearce EN

However, this extrapolation from one organ to another is questionable as the exposure levels, the phase I metabolic capacity to generate NAPQI, the phase II metabolic capacity to eliminate APAP, and potential adaptive mechanisms in response to an APAP-induced cellular stress are not well described in the CNS system

Philos Trans R Soc Lond Ser B Biol Sci 369:20130226 Gabara B, Kuniak E, Skodowska M, Surwka E, Miszalski Z (2012) Ultrastructural and metabolic modifications at the plantpathogen interface in Mesembryanthemum crystallinum leaves infected by Botrytis cinerea