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The SELECT study enrolled 17,604 individuals aged 45 years or older with existing cardiovascular disease, no T2D, and a BMI exceeding 27 kg/m 2

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Note: When symptoms occur What you ate beforehand What dose you are on Any additional medications or stressors This helps identify triggers and provides valuable information for your clinician

Notably, patients on GLP-1 RAs exhibited a 195% higher risk of major depression, a 108% increased risk for anxiety, and a 106% elevated risk for suicidal behavior

387 The SURPASS-5 trial, a 40-week study that enrolled 475 individuals with type 2 diabetes, examined the addition of tirzepatide (5 mg, 10 mg, or 15 mg once weekly) to insulin compared with insulin alone in patients treated with or without metformin