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BPC-157 first appeared in the early 1990s, when European researchers wondered why some stomach ulcers healed quickly while others didnt, Flynn McGuire, a physical medicine and rehabilitation resident at the University of Utah who is about to enter a sports medicine fellowship, tells Outside Run

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For example, a recent study published in the JAMAs Ophthalmology showed an increase in a dangerous eye condition called NAION (nonarteritic anterior ischemic optic neuropathy) for people taking semaglutide drugs for type 2 diabetes