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Side Effects & Safety Injection site reactions -- redness, swelling, stinging (common with large-volume SC injections) Flu-like symptoms -- mild fever, fatigue, malaise 24-72 hours post-injection (possibly from immune clearance of apoptotic cells) GI discomfort -- nausea, mild digestive upset Temporary fatigue -- 1-3 days post-injection Off-target cell death (theoretical) -- no compound is perfectly selective

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Stress, inflammation, and dieting can lower it further

Miyazaki, T., Hirokami, Y., Matsuhashi, N., Takatsuka, H

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Containing the active ingredient, tirzepatide, Mounjaro has become widely known for delivering impressive before-and-after transformations