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This angiogenic activity is believed to underlie a substantial part of the compounds regenerative behaviour in laboratory work, since improved vascular supply supports the delivery of nutrients to repairing tissue

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FDA status Neither TB-500 nor BPC-157 is FDA-approved for human therapeutic use

This study has significant limitations

Blocking the Notch pathway or the NF-B pathway tended to counteract the pro-angiogenic implications of TB-500 in both cell lines and murine models