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Retatrutide Side Effects & Safety Data (2026) Trial incidence for retatrutide (reta) side effects GI rates, dysesthesia, and class-level safety concerns

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The majority are mild and transient

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Gastrointestinal symptoms that some patients experience while on GLP-1 therapysuch as nausea, reduced appetite, or altered bowel habitsgenerally resolve as the medication clears from the system, typically within 1-2 weeks for short-acting formulations and within 4-8 weeks for long-acting preparations, corresponding to their elimination timelines