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Melatonin attenuates cyclophosphamide-induced primordial follicle loss by interaction with mt1 receptor and modulation of pten/akt/foxo3a proteins in the mouse ovary

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These include pericyte degeneration or reduction in pericyte coverage [54, 55], basement membrane alterations [56], and astrocytic end-feet detachment from vascular basement membrane

Quality of life, blood safety markers, and muscle biopsies for protein biomarker analysis were also conducted at baseline and the end of the study

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The Precision Peptide Genetic Test from PlexusDx analyzes key variants in genes encoding GLP-1 receptor (GLP1R rs6923761), glucose-dependent insulinotropic polypeptide receptor (GIPR rs1800437), melanocortin-4 receptor (MC4R rs17782313), and fat-mass associated gene (FTO rs9939609)