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In the large cardiovascular outcomes trial reported in the Wegovy label, systolic blood pressure fell by a mean of 3.8 mmHg with semaglutide versus 0.5 mmHg with placebo at week 104, a difference of 3.3 mmHg from a baseline of 131 mmHg

Journal of Endocrinology & Metabolism, 67 (5), 1120-1129

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Think Long-Term: Plan Ahead Check Your Progress Every 3-6 months, look at your: Weight Cravings Side effects Mood and energy Slowly Lower the Dose (If Ready) If you and your doctor decide to stop the medicine, reduce it gradually