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A sua tolerabilidade geralmente boa, embora efeitos gastrointestinais, como nusea e diarreia, possam ocorrer, principalmente no incio do tratamento (LISSI, ZANETTI, 2023)
Notably, the ICER decreased with longer time horizon, suggesting improved cost-effectiveness over time
For those curious about the "Retatrutide cost," while direct pricing isn't available, its expected to mirror current weight loss drugs costing $1,000 to $1,500 monthly
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however, it was not reported in adolescents receiving topiramate 50 or 100 mg/day
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