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The pre-blend is 3 mL for 70 mg total verify before drawing the first dose

Pregnant or breastfeeding women should avoid MOTS-c given the absence of safety data in these populations, as is standard for all investigational peptide therapies

A preferred strategy is the delivery of exogenous HGF by gene transfer, with the advantage of less side effects

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Limitations and future directions First, this study focused solely on male APP/PS1 mice, so sex-specific effects were not assessed