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Preliminary evidence that cortical amyloid burden predicts poor response to antidepressant medication treatment in cognitively intact individuals with late-life depression

The Phase 2b trial (n=536, 24 weeks) did not reach its weight-loss endpoint versus placebo, and Metabolic Pharmaceuticals discontinued obesity development in 2007

Lang, S

10.1002/stem.3383 42 HeilJ.SchultzeD.SchemmerP.BrunsH

Its the gold standard for preservation

Additionally, 425.600(h)(3) will include a limited exception for participation in the ENHANCED track by ACOs with less than 5,000 assigned beneficiaries in certain benchmark years