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Additionally, fatigue may reflect underlying metabolic changes, dehydration from gastrointestinal side effects, or pre-existing conditions such as hypothyroidism or obstructive sleep apnea (OSA), which is common in people with obesity and can significantly contribute to daytime fatigue

In SUSTAIN 6, semaglutide was associated with an increased rate of diabetic retinopathy complications, largely explained by the magnitude and speed of HbA1c reduction in people with existing retinopathy and poor baseline control, often on insulin

These systems influence how neurons communicate, how proteins are synthesized, and how cellular signals are transmitted throughout the body

Quercetin (0.08 mg/mL) and a well without an extract sample were used as positive and negative controls, respectively, for the assay reaction

Gomes, B.D