Low levels of FLNA, causing loss of coupling of SSTR2 with downstream signal transduction molecules, might explain the resistance to SS analogs in GH-secreting pituitary tumors even if in the presence of SSTR2
ii) Codd and coworkers applied PDB towards the production of a series of desferrioxamine B ( 356 ) analogs with variations in the diamine portions of the molecule, whereas semisynthetic efforts had previously only allowed for modifications to ancillary fragments chemically coupled with the natural product
doi: 10.1096/fj.202501120R 171 HanFLiSYangYBaiZ
[DOI] [PMC free article] [PubMed] [Google Scholar] 480.Giron-Michel, J
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