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Mutants lacking these enzymes show a reduced virulence in a mouse model of cryptococcosis

doi: 10.1111/rda.70079 31 AllertonTDProctorDNStephensJMDugasTRSpielmannGIrvingBA

Mechanisms of 4-hydroxy-2-nonenal induced pro- and anti-apoptotic signaling

M6 (second part of L1 and TM12) and M8 (TM16-TM17), while retaining the ability to transport GSH, were greatly impaired, mainly for M8, in their ability to transport it in a stimulated manner and consequently to sensitize cells to GSH-depleting agents