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In the 1960s, manufacturers introduced short-term weight-loss medications such as phentermine, benzphetamine, and diethylpropion, but researchers did not collect long-term safety data (8)

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Studies have shown that consistent use of Tirzepatide, in combination with a healthy diet and regular exercise, can lead to a 5% to 22.5% reduction in total body weight

Further information at doi.org/10.1016/j.chom.2025.09.007

In fertility treatments, HCG mimics the natural surges of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) to trigger ovulation and facilitate the release of a mature egg from the ovary

Outside the context of NDDs, the FDA has approved Luxturnaa transgene therapy to deliver the RPE65 gene to the retina and effectively treat a rare inherited retinal disease that results in vision impairment and blindness [48, 49]