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TNF- is found at high levels in the synovium of patients with RA [234], while IL-1 is recognized as a major contributor to inflammation in the disease [235]

Lillys Mounjaro (Tirzepatide), a GIP/GLP-1 Dual Agonist, Demonstrated Cardiovascular Protection in Landmark Head-to-Head Trial, Reinforcing Its Benefit in Patients with Type 2 Diabetes and Heart Disease (Eli Lilly and Company, accessed 19 August 2025)

What happens if I miss a dose in my first month

Obesity and Weight Management Semaglutide has been approved for chronic weight management in adults with obesity or overweight with at least one weight-related condition, such as hypertension or dyslipidemia

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More studies are ongoing to understand further the full extent of semaglutide's cardiovascular benefits and potential uses in other cardiovascular-risk populations