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To evaluate Dihexas ability to cross the BBB and accumulate in brain regions, rats were fitted with carotid cannulas and infused with a mixture of [H]Dihexa (10 Ci) and [C]inulin (2 Ci), a vascular space marker, in 100 l of isotonic saline

Biochem Pharmacol 2000

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Moreover, studies show that neither kidney nor liver function have an effect on the level of tirzepatide in your system

Their mechanisms arent entirely understood

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