Levels of estrogen and progesterone shift unevenly and unpredictably through perimenopause, causing hormonal symptoms, which include: Irregular periods and reduced fertility Hot flashes Insomnia Night sweats Changes in mood: depression, mood swings, and irritability Changes in sexual function: vaginal dryness and atrophy, painful intercourse, low libido, reduced sexual arousal, difficulty achieving orgasm Weight gain Breast tenderness Brain fog, forgetfulness, and difficulty concentrating (7, 30) Reductions in estrogen levels are also associated with increased risk for vaginal and urinary tract infections, osteopenia, osteoporosis, dyslipidemia, and heart disease (39)
Without rigorous testing, it's unknown if the compounds could have unintended, harmful effects, says Eileen Kennedy, a chemical biologist at the UNC Eshelman School of Pharmacy who studies peptide therapies
Since both of these vitamins are fat-soluble, consuming them with fat-containing foods helps improve their absorption in the body
Non-oral contraceptive methods offer reliable alternatives that bypass concerns about gastrointestinal absorption entirely
The human peptide GHK has high Cu2+ affinity and readily binds with copper in the body, thus creating GHK-Cu
Nazareth suggests keeping a strict bedtime routine: settling in at the same time each night, avoiding electronics, caffeine, food, alcohol, and intense conversations close to bedtime
