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It was effectively applied either immediately (prophylactically) after paracetamol challenge or (therapeutically) administered after a 3 h period had elapsed (note, the maximum depletion of hepatic glutathione occurred 3 h after acute paracetamol dosing (37))

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Finkley MB et al

So EMS may have a place, but it is not a substitute for actually moving

In 2014, the FDA granted AOD 9604 Human GRAS (Generally Recognized As Safe) status, indicating a favorable safety profile when used as directed

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