Among these diverse hormone-based therapies, tirzepatide, a dual GLP-1 and GIP receptor agonist with activity biased towards GIP, has demonstrated superior weight-loss efficacy across multiple clinical trials [38]
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(1) Like other weight loss medications, it would be administered as a once-weekly injection, inserted subcutaneously into areas such as the arms, thighs, or abdomen
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They assist in reestablishing immune homeostasis in the reproductive tract by promoting a shift in macrophage and T-cell phenotypes toward regulatory, which supports tolerance during implantation and avoids immune-mediated gamete injury
Secondly, it stimulates blood vessel and nerve growth and improves tissue repair