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siRNA knockdown Macrophages (2.5 10 5 cells/mL) were seeded for 24 h and then were transfected with 10 nM of small interfering RNA (siRNA, GPx1 s804, s805, Thermo Fisher Scientific) or a negative control (Silencer Select siRNA Negative control 4394803, Thermo Fisher Scientific) following the manufacturers instructions

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Acknowledgments The authors thank Judit Planas Carbonell, Claudia Savoia, and Jean-Denis Courcol for organizing web portal development and visualization and Matthias Wolf for software support

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