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L-aspartate displayed a high fold-change (Rao et al., 2021)

Delivery intervals are diverse, too, ranging from as little as two weeks to as long as six months

It further suggests that disruption of hypothalamic pathways involved in appetite and energy homeostasis may result in alterations in other pathways such as GLP-1-mediated signaling in the brainstem, which remain intact in HO patients