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(5.10) Adverse Reactions/Side Effects The most common adverse reactions reported in 5% of patients treated with OZEMPIC are: nausea, vomiting, diarrhea, abdominal pain and constipation

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Statistical analysis Descriptive statistics Descriptive statistics are presented as numbers and proportions (%), means and standard deviations (SD), or medians and interquartile ranges (IQR)

This was highlighted in an experimental study performed on GLP-1-treated HL-1 cardiomyocytes, in which GLP1 increased calcium transients and sarcoplasmic reticular calcium contents by regulating the expression of calcium handling proteins, leading to a reduced calcium leak and thus preventing AF development [34]