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Break any step, and absorption fails
People who were overweight or obese lost significant weight while taking retatrutide, which enabled them to be more active and reduced knee pain by an average of 4.5 points or about 76% based on pain scores from whats known as the Western Ontario and McMaster Universities Osteoarthritis Index
But many of the other peptides you can buy are, at best, experimental, and their purported benefits are unproven
More recent research has explored AOD9604 for other potential applications beyond obesity, including osteoarthritis treatment based on observations of cartilage regeneration properties in preclinical models, though clinical validation of these additional indications is limited