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First, rapid dose escalation increases the likelihood and severity of GI side effects, which are particularly problematic for patients with IBD, celiac disease, or other GI-affecting autoimmune conditions

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It's often a side effect of eating less, not a deliberate choice

In Vance DE, Vance J (eds.)

Patients should seek immediate medical attention for severe abdominal pain (which may indicate pancreatitis), symptoms of gallbladder disease, signs of dehydration, allergic reactions, or any unusual neck mass or swelling