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The main mechanism of cardioprotective effects of GLP-1R agonists against oxidative stress-induced injury in H9c2 cells (cardiomyoblasts from Rattus norvegicus) and in cardiomyocytes is related to the scavenging of reactive oxygen species, by increasing the concentrations of endogenous antioxidant defenses and inhibiting cardiomyocyte apoptosis [42]

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Next, the cells (1 10 6 cells/mL) were transferred to Erlenmeyer flasks and transfected with a viral stock encoding the His-tagged soluble human FcRn kindly provided by Dr

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