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Exposure to toxins, chemicals, or heavy metals may also disrupt immune tolerance

Dedicated clinical trials in adults 70 and older that include body composition and functional outcomes as primary endpoints are urgently needed and beginning to be funded

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Low-grade inflammation as a risk factor for cardiovascular events and all-cause mortality in patients with type 2 diabetes

Adv Drug Deliv Rev 123:317 Kim DE, Pruskowski KA, Ainsworth CR, Linsenbardt HR, Rizzo JA, Cancio LC (2019) A review of adjunctive therapies for burn injury pain during the opioid crisis