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The Critical Mistake: What is Lean Mass? Now, heres one shocking fact: no study had yet directly explored how incretin-based poly-agonists, tirzepatide (GLP-1-GIP) and retatrutide (GLP-1-GIP-Glucagon) affect skeletal muscle

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Researchers attribute the differential signal in part to the additive GCGR-mediated energy expenditure contribution

Patients taking insulin or sulfonylureas may need dose reductions of these medications to prevent hypoglycaemia as GLP-1 therapy improves glucose control

Pandya CD, Kutiyanawalla A, Pillai A

Semaglutide GLP-1 effectiveness in inducing weight loss has been observed, making it a popular choice for many of our patients