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The peptide is constructed on a GIP receptor backbone with non-coded amino acid residues (Aib2, Aib20, aMeL13) and a C20 fatty diacid moiety that enables albumin binding, extending pharmacokinetic half-life for once-weekly administration in research settings

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Unlike peptides, aromatic organic molecules can naturally absorb portions of visible light

DHCA and Mal-gluc, as externalizing metabolites of bioactive dietary polyphenol compounds, have been associated with depression [98], and in addition to modulating neurexins and synaptic plasticity, studies on their further sustained antidepressant activity should follow

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Retrieved September 1, 2020