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doi: 10.1016/S0736-0266(03)00110-4

National Library of Medicine, 31 July 2025

Abstract Glutathione-mediated biotransformation in the liver is a well-known detoxification process to eliminate small xenobiotics, but its impacts on nanoparticle retention, targeting and clearance are much less understood than liver macrophage uptake, even though both processes are involved in liver detoxification

(Regulatory Toxicology and Pharmacology, 2020) reported a preclinical safety package designed to support potential drug development