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The mitochondrial enzyme ALA synthase (ALAS) initiates the rate-limiting condensation of succinyl-coenzyme A and glycine to form 5-aminolevulinate (ALA) 26

The inhibitor STM2457 can reduce the m6A level in cancer cells by inhibiting the IGFBP3/AKT signaling axis, thus exerting anticancer effects in vitro and in vivo (127)

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