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However, our natural production of glutathione is not infinite

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doi: 10.1007/s10637-011-9763-9 148 CarvajalRDLawrenceDPWeberJSGajewskiTFGonzalezRLutzkyJet al

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Furthermore, the precise stereochemistry of the AEEA and -Glu linkers requires specialized orthogonal protection schemes during synthesis