Stress, food allergies, alcohol, antibiotics, malnutrition are some of the factors that lead to leaky gut syndrome
National Toxicology Program
Abstract Curcumin (1,7-bis-(4-hydroxy-3-methoxyphenyl)-hepta-1,6-diene-3,5-dione) is a naturally occurring polyphenol molecule
4.1 Tumor glycolytic metabolism and immune response The metabolites and waste products excreted by tumor cells (lactate, CO 2 , H + , NH4 + , nitric oxide, butyrate, polyamines, and ROS, among others) establish acidification of the microenvironment, that is, compatible with cell proliferation and dissemination, promoting several processes such as decreased cell adhesion, angiogenesis, and mesenchyme-epithelial transition (MET) in other tumor models
M.LiC.PoulogiannisG.ChooA
This is because of the unique ability of glutathione amino acid precursors to protect cells and catalyze the elimination of xenobiotics