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Food helps but is not equivalent to drugs that directly and strongly activate GLP-1 receptors

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However, consuming particularly high doses of vitamin B12that is, more than the recommended 2.4 micrograms per daycan cause side effects headaches, fatigue, weakness, and tingling in extremities to gastrointestinal symptoms such as diarrhea, nausea, and vomiting

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Through these mechanisms of action, GLP-1 RAs (exenatide, lixisenatide, liraglutide, dulaglutide, albiglutide, semaglutide) strengthen the physiological effect of endogenous GLP-1