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Xue Q, Wang Y, Zheng Q, Chen L, Jin Y, Shen X, Li Y

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Recent studies have demonstrated that FNDC5 expression and secretion of irisin from adipocytes is lower in patients with obesity and T2D than in lean controls [41]

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Please see also the XGBoost documentation for additional information on model parameters ( SHapley additive exPlanations (SHAP) analysis We interpreted our ML models and assigned relative importance to variables influencing circulating TMAO levels by co-opting SHAP values, as expanded for tree-based ML models 28 and recently used to objectively evaluate factors driving metabolite plasma levels in humans 23

K., & Molin, S