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Thus, disturbances in mitochondrial ICS biosynthesis could contribute to failures in the supply of energy (which might result in cell death) or to cancer, since genomic instability is considered as a hallmark of cancer and a driver of neoplastic transformation processes

10.1096/fj.202402648RR 73 ZhangM.ShiYangX.ZhangY.MiaoY.ChenY.CuiZ.et al (2019)

A chaperone-proteasome-based fragmentation machinery is essential for aggrephagy

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It is available as follows: Acetylcysteine 10% solution (100 mg acetylcysteine per mL)