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Introducing a wide-ranging AMA: practical perspectives on lifespan interventions, metabolic health, diet, hormones, diagnostics, and more [2:45]

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no established oral bioavailability Tendon, ligament, bone, and gastrointestinal healing

Clinical trials show the mix produces superior gains in HbA1c (a measure of long-term glucose control), fasting glucose, and postprandial glucose compared to semaglutide monotherapy

Randomized trials that isolated B12 tend to be small or combine the vitamin with other agents, making causal claims weak

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