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Glucagon-like peptide-1 (GLP-1) is an incretin hormone, one of several gut-derived peptides secreted in response to nutrient intake that promote insulin release

However, both influence body composition and metabolic function, meaning their combined effect on weight loss, muscle retention, and energy expenditure requires careful coordination with your prescribing physician

While the safety of GLP-1 RAs is well established, current scientific evidence on the efficacy of microdosing GLP-1 RAs is lacking and further research is required to assess its benefits at lower doses

More research should be done to monitor side effects and see if it also has the benefits of other GLP-1 medications, such as preventing cardiac events, Mir Ali, MD, bariatric surgeon and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, CA, agreed

(2023, April 17)