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Temporal Analyses of Postnatal Liver Development and Maturation by Single Cell Transcriptomics

Severe B12 deficiency (not often seen in our modern farming systems) results in runty lambs in extremely poor condition, despite good feed levels

Cognitive function in obese individuals improves substantially with weight loss alone, but the direct central GLP-1R effects may contribute additional benefit beyond what weight reduction alone would predict

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This knowledge informs both protocol design and the interpretation of research outcomes

New additions (Sodium glucose transporter 2 inhibitors [SGLT2i/Flozin] and non-steroidal mineralocorticoid antagonists [nsMRAs]) to the bedrock of RAS inhibition (RASi) covered more territory and improved outcomes