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Range of ocular complications extends beyond NAION In addition to NAION, the report notes that GLP-1RAs may worsen age-related macular degeneration and accelerate diabetic retinopathy progression

This distinction becomes important when considering whether combining both approaches could yield synergistic benefits or redundant effects

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Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects

Dose appears to matter: the effect on drinking in the Lancet trial appeared at the full 2.4 mg dose, while the lower-dose JAMA Psychiatry trial found weaker real-world effects

Strength Training on GLP-1: Why Its Essential Maintain your muscle and health while losing body fat