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For most people, this occurs within 2-3 months

Metabolic therapies such as GLP-1s primarily influence inflammation, mitochondrial function, and nutrient signaling, while other pharmacological or lifestyle strategies may act on telomere maintenance [16], senescence biology [17], or epigenetic regulation [18]

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The concurrent decrease in glucose and insulin levels suggests improved glycemic control and enhanced insulin sensitivity

Biol Reprod (2000) 63(5):128593