Direct nutrient stimulation may induce the initial release of GLP-1 from small intestinal EECs, while large intestinal EECs likely release GLP-1 via a neural hormonal reflex or from microbe-derived metabolites, although this remains to be explored 93,99 (see the Gut microbiotabrain connection section)
doi: 10.1186/1471-2350-15-75
Its role in the adult brain involves supporting neuronal survival, promoting synaptic plasticity, and facilitating neurogenesis -- functions that make it a plausible target for cognitive enhancement
What to Know About Menopausal Hormone Therapy and GLP-1s Peri-menopause is a transition that women typically start in their 40s
(Kennedy and Wightman, 2011)
If you believe you are experiencing a medical emergency, call your local emergency services or go to your nearest emergency department