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These metabolites are biologically active, can reduce intravascular oxidative stress, inhibit hepatocyte gluconeogenesis and oxidative stress, increase cardiomyocyte activity, promote vasodilation, protect the cardiovascular system, improve cardiac function, thereby directly or indirectly protecting the cardiovascular system ( 4.3 Nervous system disorder Recently, a protective effect of the GLP-1/GLP-1R axis on ischemic brain injury has been emphasized

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Benefits for insulin resistance and PCOS Semaglutide does more than help with weight loss it works great for patients with insulin resistance and polycystic ovary syndrome (PCOS)

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In the meantime, people taking GLP-1 agonists for weight loss may need to lean on old fashioned methods for retaining muscle exercise and a healthy diet and there are groups trying to make this easier