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The heart-rate cost is mostly the glucagon arm: GLP-1 on its own nudges heart rate up a little and then flattens, while glucagon carries the part that keeps climbing with the dose

Zepbound doses include 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg (maximum dose)

Switching to a non-GLP-1 medication This transition requires the most caution

Fewer have accurate information

Mol Cell Biol 14(9):58325839 Wu J, Qu T, Chen S, Zhao Z, An L (2009) Molecular cloning and characterization of a -glutamylcysteinesynthetase gene from Chorispora bungeana

pylori s propensity to generate DNA strand breaks undoubtedly contributes to genomic instability and may aid in carcinogenesis (77)