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Patient-derived xenografts (PDXs) and genetically engineered mouse models (GEMMs) offer more physiological insights but are limited by cost, long development times, and species-specific differences [40,41,42]

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When inflammation is the baseline rather than a short event, KLOW is the cleaner fit

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In laboratory studies, scientists often test the capsules in biological systems

From a neuroscience perspective, these interventions help the brain transition more safely back toward equilibrium rather than forcing an abrupt and overwhelming recalibration